Bone Tissue Engineering



Selected Publications:

S/N Journal Paper
1. DW Hutmacher, JT Schantz, I Zein, KW Ng, SH Teoh and KC Tan, Mechanical properties and cell cultural response of polycaprolactone scaffolds designed and fabricated via fused deposition modeling, J Biomed Mat Res, 55 (2001): 203-216.
2. I Zein, DW Hutmacher, KC Tan and SH Teoh, Fused deposition modeling of novel scaffold architectures for tissue engineering applications, Biomaterials, 23 (2002): 1169-1185.
3. CXF Lam, XM Mo, SH Teoh and DW Hutmacher, Scaffold Development using 3D Printing with a Starch Based Polymer, Mat Sci and Eng: C (Special Issue on Biomaterials and Tissue Engineering): 20 (2002): 49-56.
4. ZY Cheng and SH Teoh, Surface modification of ultra thin poly (e-caprolactone) films using acrylic acid and collagen, Biomaterials 25 (2004): 1991–2001.
5. HW Ouyang, JCH Goh, A Thambyah, SH Teoh and EH Lee, Knitted PLGA scaffold loaded with bone marrow stromal cells in repair and regeneration of rabbit Achilles tendon, Tissue Engineering, 9 no 3 (2003) : 431-439
6. TH Ang, FSA Sultana, DW Hutmacher, YS Wong, JYH Fuh, XM Mo, HT Loh, E Burdet and SH Teoh, Fabrication of 3D chitosan-hydroxyapatite scaffolds using a robotic dispensing system, Mat Sci and Eng: C (Special Issue on Biomaterials and Tissue Engineering): 20 (2002): 35-42
7. DW Hutmacher, JCH Goh and SH Teoh, An introduction to biodegradable materials for tissue engineering applications, Ann. Acad. Med. Singapore, 30 no.2 (2001): 183-191
8. SH Teoh, Fatigue of biomaterials: A review, Int J. Fatigue, (Special Issue on Biomaterials): 22 (2000): 825-837.
9. B Rai, SH Teoh, DW Hutmacher, T Cao and KH Ho, Novel PCL-based honeycomb scaffolds as drug delivery systems for rhBMP-2, Biomaterials, 26 (2005): 3739-3748
10. B Rai, ME Oest, KM Dupont, KH Ho, SH Teoh and RE Guldberg, Combination of platelet-rich plasma with polycaprolactone-tricalcium phosphate scaffolds for segmental bone defect repair, J Biomed Mats Res. Part A, 81A (2007): 888-899.

Recent Publications:

S/N Journal Paper
1. Teo L, Teoh SH, Liu Y, Lim L, Tan B, Schantz JT, Seah LL. A Novel Bioresorbable Implant for Repair of Orbital Floor Fractures. Orbit (2015): 1-9.
2. Chong, M.. Experimental models of bone metastasis: opportunities for the study of cancer dormancy. Advanced drug delivery reviews (2015).
3. Goh BT, Teoh KH. Orbital implant placement using a computer-aided design and manufacturing (CAD-CAM) stereolithographic surgical template protocol. Int J Oral Maxillofac Surg (2015): 642-648.
4. Zhang T, Wen F, Wu Y, Goh GS, Ge Z, Tan LP, Hui JH, Yang Z. Cross-talk between TGF-beta/SMAD and integrin signaling pathways in regulating hypertrophy of mesenchymal stem cell chondrogenesis under deferral dynamic compression. Biomaterials (2015): 72-85.
5. Wang, Z.Y., J. Lim, Y.S. Ho, Q.Y. Zhang, M.S. Chong, M. Tang, M.H. Hong, J.K. Chan, S.H. Teoh, and E.S. Thian. Biomimetic three‐dimensional anisotropic geometries by uniaxial stretching of poly (ε‐caprolactone) films: Degradation and mesenchymal stem cell responses. Journal of Biomedical Materials Research Part A (2014): 2197-2207.
6. Lim, J., M.S.K. Chong, J.K.Y. Chan, and S.H. Teoh. Polymer Powder Processing of Cryomilled Polycaprolactone for Solvent‐Free Generation of Homogeneous Bioactive Tissue Engineering Scaffolds (2014): 2495-2502.
7. Lim W, Lye KW, Goh BT. Osteochondroma of mandibular condyle: report of 2 surgical approaches. Ann Maxillofac Surg (2014): 215-219.
8. Goh BT, Chanchareonsook N, Tideman H, Teoh SH, Chow JKF, Jansen JA. The use of a polycaprolactone–tricalcium phosphate scaffold for bone regeneration of tooth socket facial wall defects and simultaneous immediate dental implant placement in Macaca fascicularis. J Biomed Mater Res Part A (2014):1379–1388.
9. Yang X, Muthukumaran P, DasDe S, Teoh SH, Choi H, Lim SK and Lee T. Positive alterations of viscoelastic and geometric properties in ovariectomized rat femurs with concurrent administration of ibandronate and PTH. Bone (2013): 308-317.
10. Liu Y, Hsu CYS, Teo CMJ, and Teoh SH. Potential Mechanism for the Laser-Fluoride Effect on Enamel Demineralization. Journal of Dental Research (2013): 71-75.
11. Liu Y, Hsu CYS, Teo CMJ and Teoh SH. Subablative Er:YAG Laser Effect on Enamel Demineralization. Caries Research (2013): 64-68.
12. Lim J, Chong MSK, Teo EY, Chen GQ, Chan JKY and Teoh SH. Biocompatibility studies and characterization of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate)/ poly-caprolactone blends. Journal of Biomedical Materials Research Part B: Applied Biomaterials (2013):752-761.
13. Yeo A, Cheok C, Teoh SH and Zhang ZY, Buser D, and Bosshart DD. Lateral ridge augmentation using a PCL-TCP scaffold in a clinically relevant but challenging micropig model. Clinical Oral Implants Research (2012): 1322-1332.
14. Liu YC, Lim J, and Teoh SH. Review: Development of clinically relevant scaffolds for vascularised bone tissue engineering. Biotechnology Advances (2012): 688-705.
15. Liu YC, Chan KYJ and Teoh SH. Review on vascularised bone tissue engineering strategies: focus on co-culture systems. Journal of Tissue Engineering and Regenerative Medicine (2012): 85-105.
16. Liu YC, Teoh SH, Chong M, Yeow CH, Kamm RD, Choolani M and Chan KYJ. Contrasting effects of vasculogenic induction upon biaxial bioreactor stimulation of mesenchymal stem cells and endothelial progenitor cells co-cultures in 3D scaffolds under in vitro and in vivo paradigms for vascularized bone tissue engineering. Tissue Engineering (2012): 893-904.
17. JC Teo and SH Teoh. Permeability study of vertebral cancellous bone using micro-computational fluid dynamics, Comput Methods Biomech Biomed Engin. Comput Methods Biomech Biomed Engin (2012): 417-423.
18. Zhang ZY; Teo, SH; Hui JHP; Fisk NM; Choolani M; Chan JKY. The potential of human fetal mesenchymal stem cells for off-the-shelf bone tissue engineering application. Biomaterials (2012): 2656-2672.
19. Schantz-Jan Thorsten; Machens Hans-Guenther; Schilling Arndt F.; Teoh Swee Hin. Regenerative Medicine: Implications for Craniofacial Surgery. Journal of Craniofacial Surgery (2012): 530-536.
20. Zhang ZY, Pei GX, Teoh SH and Chan J. Development of a clinically feasible off-the-shelf bone tissue engineering strategy with the integrated use of human fetal mesenchymal stem cells, polycaprolactone scaffolds and a bi-axial rotating bioreactor. Journal of Tissue Engineering and Regenerative Medicine (2012): 26-27.
21. Teoh SH; Liu YC and Chan JKY. Strategies for vascularised bone tissue engineering: combining honeycombed-like scaffolds, biaxial bioreactor, growth factors, co-culture of stem cells. Journal of Tissue Engineering and Regenerative Medicine (2012): 21-22.
22. Liu YC, Chan J, Chong M, Choolani M and Teoh SH.The importance of continuous hypoxic exposure for the culture of human fetal mesenchymal stem cells in bone tissue engineering applications. Journal of Tissue Engineering and Regenerative Medicine (2012): 28.
23. Zhang Z, Egaña JT, Reckhenrich AK, Schenck TL, Lohmeyer JA, Schantz JT, Machens HG. Schilling AF Cell-based resorption assays for bone graft substitutes. Acta Biomater (2012): 13-9.


                                                                                                                              Updated on 15 October 2015